A new factor V gene polymorphism (His 1254 Arg) present in subjects of african origin mimics the R2 polymorphism (His 1299 Arg)
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منابع مشابه
P-93: Analysis of P53 Codon 72 Gene Polymorphism in Isfahanian Patients With Endometriosis
Background: The p53 tumor suppressor gene plays important roles in genomic stability. Several reports have noted racial differences in the prevalence of p53 genotypes at the codon 72 in patients with endometriosis.To study the association of endometriosis with p53 codon 72 polymorphism in the population of Isfahan. Materials and Methods: We undertook a case–control study to examine the possible...
متن کاملCodon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus
Background: Systemic lupus erythematosus is a systemic autoimmune disorder with unclear etiology. The importance of some genes in the development of systemic lupus erythematosus has been implicated. The gene polymorphism in codon 72 has attracted a lot of attention and its role in the occurrence or progression of many cancers and autoimmune diseases especially systemic lupus erythematosus has ...
متن کاملAnalysis of TP53 Codon 72 Polymorphism in Mucinous and Non-Mucinous Colorectal Adenocarcinoma in Isfahan, Iran
Background: The tumor suppressor gene TP53 (alias p53) located on chromosome 17 is involved in various cancers. Case-control studies have shown that p53 codon 72 polymorphism modulates the prognosis and susceptibility to various malignancies. We undertook the present study to explore a possible association between mucinous and non-mucinous adenocarcinomas with different genotypes or alleles at ...
متن کاملبررسی مقایسه‌ای فراوانی پلی‌مورفیسم Gln/Arg192آنزیم پارااکسوناز1 در افراد مبتلا به گرفتگی عروق کرونری و گروه کنترل
Background & Aim: Serum paraoxonase (PON1) is an HDL (high density lipoprotein) associated esterase that prevents the oxidation of LDL (low density lipoprotein). A common polymorphism in coding region of the paraoxonase gene involving a Gln (Q) to Arg (R) interchange at position 192 has been demonstrated to affect PON1 activity. It has been shown that R alloenzyme is less efficient at prevent...
متن کاملA Pilot Study of Polymorphism of Adrenergic Beta-2 Receptor and Mild Asthma: A Clinical and Pharmacogenetic Study
Glycine allele at codon 16 has previously been associated with the increase in asthma severity, bronchial hyperresponsiveness and also the increase in inhaled corticosteroid dependence. This study was designed to evaluate the genetic alleles in mild asthma.Thirty-four patients with diagnosis of mild asthma (FEV1 ≥ 80%, positive methacholine test) and body mass index (BMI ≤ 30 Kg/m2) were includ...
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ورودعنوان ژورنال:
- Blood
دوره 91 1 شماره
صفحات -
تاریخ انتشار 1998